- Abstract:
-
The basic helix-loop-helix (bHLH) factor Hand1 plays an essential role in cardiac morphogenesis, and yet its precise function remains unknown. Protein-protein interactions involving Hand1 provide a means of determining how Hand1-induced gene expression in the developing heart might be regulated. Hand1 is known to form either heterodimers with near-ubiquitous E-factors and other lineage-restricted class B bHLH proteins or homodimers with itself in vitro. To date, there have been no reported Ha...
Expand abstract - Publisher copy:
- 10.1128/mcb.24.22.9835-9847.2004
-
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- Journal:
- Molecular and cellular biology
- Volume:
- 24
- Issue:
- 22
- Pages:
- 9835-9847
- Publication date:
- 2004-11-05
- DOI:
- EISSN:
-
1098-5549
- ISSN:
-
0270-7306
- URN:
-
uuid:180d83fb-6936-484f-b38c-eff181654965
- Source identifiers:
-
251927
- Local pid:
- pubs:251927
- Language:
- English
- Keywords:
- Copyright date:
- 2004
Journal article
Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2.
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