Journal article

Field-based flow cytometry for ex vivo characterization of Plasmodium vivax and P. falciparum antimalarial sensitivity.

Abstract:: Ex vivo antimalarial sensitivity testing in human malaria parasites has largely depended on microscopic determination of schizont maturation. While this microscopic method is sensitive, it suffers from poor precision and is laborious. The recent development of portable, low-cost cytometers has allowed us to develop and validate a simple, field-optimized protocol using SYBR green and dihydroethidium for the accurate and objective determination of antimalarial drug sensitivity in freshly isolated Plasmodium vivax and Plasmodium falciparum.

Publication status:: Published

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APA Style

Russell, B., Malleret, B., Suwanarusk, R., Anthony, C., Kanlaya, S., Lau, Y., Woodrow, C., Nosten, F., & Renia, L. (2013). Field-based flow cytometry for ex vivo characterization of Plasmodium vivax and P. falciparum antimalarial sensitivity. Antimicrobial Agents and Chemotherapy, 57(10), 5170–5174.

MLA Style

Russell, B, et al. “Field-Based Flow Cytometry for Ex Vivo Characterization of Plasmodium Vivax and P. Falciparum Antimalarial Sensitivity.” Antimicrobial Agents and Chemotherapy, vol. 57, no. 10, 2013, pp. 5170–74.

Chicago Style

Russell, B, B Malleret, R Suwanarusk, et al. 2013. “Field-Based Flow Cytometry for Ex Vivo Characterization of Plasmodium Vivax and P. Falciparum Antimalarial Sensitivity.” Antimicrobial Agents and Chemotherapy 57 (10): 5170–74.
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Publisher copy:: 10.1128/aac.00682-13

Authors

+ Russell, B More by this author

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+ Malleret, B More by this author

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+ Suwanarusk, R More by this author

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+ Anthony, C More by this author

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+ Kanlaya, S More by this author

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Journal:: Antimicrobial agents and chemotherapy More from this journal
Volume:: 57
Issue:: 10
Pages:: 5170-5174
Publication date:: 2013-10-01
DOI:: 10.1128/aac.00682-13
EISSN:: 1098-6596
ISSN:: 0066-4804

Language:: English
Keywords:: Flow Cytometry

Plasmodium falciparum

Antimalarials

Plasmodium vivax
Pubs id:: pubs:414662
UUID:: uuid:17f5ff66-8225-49e3-90f4-8ddb0608f60c
Local pid:: pubs:414662
Source identifiers:: 414662
Deposit date:: 2014-02-08
ARK identifier:: ark:/29072/ora_17f5ff66822549e390f48ddb0608f60c

Terms of use

Copyright date:: 2013

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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