Coherent cortical and muscle discharge in cortical myoclonus.

Journal article

There is increasing evidence in man that the cortical drive to motor neurons is rhythmic. This oscillatory drive may be exaggerated in patients with cortical myoclonus. Spectral analysis of surface bipolar EEG and EMG activity was performed in eight such patients. Only three cases had evidence of giant cortical evoked potentials or a cortical correlate on back-averaging at the time of study. In six subjects, significant coherence between contralateral and vertex EEG and EMG was observed in ra...

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Authors: Brown, P; Farmer, S; Halliday, D; Marsden, J; Rosenberg, JR

• Publication status: Published
• Journal: Brain : a journal of neurology
• Volume: 122 ( Pt 3)
• Issue: 3
• Pages: 461-472
• Publication date: 1999-03-01
• DOI: 10.1093/brain/122.3.461
• EISSN: 1460-2156
• ISSN: 0006-8950
• Language: English
• Keywords: Female; Evoked Potentials, Motor; Adult; Muscle, Skeletal; Male; Periodicity; Adolescent; Aged; Electromyography; Cerebral Cortex; Magnetoencephalography; Middle Aged; Myoclonus; Humans; Electroencephalography; Anticonvulsants