In recent years genome-wide scans and association studies for schizophrenia susceptibility genes have been published. Some have yielded significant positive findings, but there is disagreement between studies concerning their location. No mutation in any gene has yet been found. Since schizophrenia is a complex disorder, a study with sufficient power to detect a locus with small or moderate gene effect is necessary. We have thus conducted a genome-wide scan of 382 sibling pairs each with a di...