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Journal article

Nitric oxide synthase isoforms play distinct roles during acute peritonitis.

Abstract:

BACKGROUND: Acute peritonitis is the most frequent complication of peritoneal dialysis (PD). Increased nitric oxide (NO) release by NO synthase (NOS) isoforms has been implicated in acute peritonitis, but the role played by the NOS isoforms expressed in the peritoneum is unknown. METHODS: We investigated the structural and functional consequences of acute peritonitis induced by LPS in wild-type (WT) mice versus knockout mice (KO) for the endothelial NOS (eNOS), the inducible NOS (iNOS) or th...

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Publication status:
Published

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Publisher copy:
10.1093/ndt/gfp415

Authors


McLoughlin, RM More by this author
Brodovitch, A More by this author
Brouckaert, P More by this author
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Journal:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Volume:
25
Issue:
1
Pages:
86-96
Publication date:
2010-01-05
DOI:
EISSN:
1460-2385
ISSN:
0931-0509
URN:
uuid:17de081e-c13d-4897-a23f-f1b185445476
Source identifiers:
105373
Local pid:
pubs:105373

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