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Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis.

Abstract:

The effects upon regional brain function of infusing either saline or clonidine (1.5 microgram/kg) has been examined in 18 patients with alcoholic Korsakoff's psychosis using 99mTc-hexamethylpropyleneamineoxime (99mTc-HMPAO or 99mTc-Exametazime) and Single Photon Emission Tomography (SPET or SPECT). The hypothesis tested was that frontal lobe function would be increased by adrenoceptor stimulation. This was confirmed by an increase in the uptake of 99mTc-Exametazime into anterior cingulate re...

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Authors


Moffoot, A More by this author
O'Carroll, RE More by this author
Dougall, N More by this author
Ebmeier, K More by this author
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Journal:
Psychological medicine
Volume:
24
Issue:
1
Pages:
53-61
Publication date:
1994-02-05
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:17dd52d4-faf4-4623-8207-e310d329fb32
Source identifiers:
139292
Local pid:
pubs:139292

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