Journal article icon

Journal article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Abstract:

Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population. In a genome-wide search for loci associated with the upper versus the lower 5th percentiles of body mass index, height and waist-to-hip ratio, as well as clinical classes of obesity, including up to 263,407 individuals of European ancestry, we identified 4 new loci (IGFBP4, H6PD, RSRC1 and PPP2R2A) influ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/ng.2606

Authors


Expand authors...
Journal:
Nature Genetics
Volume:
45
Issue:
5
Pages:
501-512
Publication date:
2013-05-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:17b64cdb-b6d0-4a47-a3a9-b4dd693bb576
Source identifiers:
402672
Local pid:
pubs:402672
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP