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Lymph node macrophage heterogeneity: the phenotypic and functional characterization of two distinct populations of macrophages from rat lymph node.

Abstract:

The isolation and characterization of lymph node macrophages (M phi) has shown a hitherto unknown heterogeneity. Two types of M phi were distinguished by morphology, monoclonal antibody staining and functional assays. The type I M phi failed to express surface Ia even when activated, a characteristic which has only previously been reported for splenic marginal zone M phi; despite studies suggesting an antigen presentation role for the M phi, the failure to express surface Ia would seem to eli...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830190719

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
European journal of immunology
Volume:
19
Issue:
7
Pages:
1273-1281
Publication date:
1989-07-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:17b28d6d-cfb8-4b26-876f-cb3a9764eb16
Source identifiers:
25953
Local pid:
pubs:25953

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