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Combination therapy: Making the best use of existing drugs

Abstract:

The spread of multi-drug resistance in P. falciparum limits the choice of effective antimalarial drugs in many endemic areas. The efficacy of the major antimalarial drugs has declined in recent years, in particular in South East Asia where P. falciparum has developed resistance to chloroquine, sulfadoxine- pyrimethamine and mefloquine. The use of combinations in antimalarial treatment could prevent or at least delay antimalarial drug resistance as the chance of selecting a drug resistant muta...

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Authors


Pukrittayakamee, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
Pharmaceutical News
Volume:
8
Issue:
5
Pages:
21-26
Publication date:
2001
ISSN:
1071-894X
URN:
uuid:178d42f5-db4f-4d4a-ac2a-a0d7a8c8a606
Source identifiers:
95530
Local pid:
pubs:95530
Language:
English
Keywords:

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