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Journal article

Treatment of neonatal sepsis with intravenous immune globulin.

Abstract:

BACKGROUND: Neonatal sepsis is a major cause of death and complications despite antibiotic treatment. Effective adjunctive treatments are needed. Newborn infants are relatively deficient in endogenous immunoglobulin. Meta-analyses of trials of intravenous immune globulin for suspected or proven neonatal sepsis suggest a reduced rate of death from any cause, but the trials have been small and have varied in quality. METHODS: At 113 hospitals in nine countries, we enrolled 3493 infants receivin...

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Publication status:
Published

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Publisher copy:
10.1056/nejmoa1100441

Authors


Brocklehurst, P More by this author
Farrell, B More by this author
Juszczak, E More by this author
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Journal:
The New England journal of medicine
Volume:
365
Issue:
13
Pages:
1201-1211
Publication date:
2011-09-05
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:177e47d4-b46b-427e-8e53-332c96267851
Source identifiers:
255976
Local pid:
pubs:255976

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