- Abstract:
-
MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencies of 'memory' T cell responses against viruses such as cytomegalovirus (CMV) and Epstein-Barr virus (EBV), and provided information about their phenotypic and functional variation. However, such studies have...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1046/j.1365-2249.2003.02266.x
-
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- Journal:
- Clinical and experimental immunology
- Volume:
- 134
- Issue:
- 1
- Pages:
- 9-12
- Publication date:
- 2003-10-05
- DOI:
- EISSN:
-
1365-2249
- ISSN:
-
0009-9104
- URN:
-
uuid:176bf23e-9d71-4de2-8ca9-79eba1733e8c
- Source identifiers:
-
13691
- Local pid:
- pubs:13691
- Language:
- English
- Keywords:
- Copyright date:
- 2003
Journal article
Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.
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