Journal article icon

Journal article

Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.

Abstract:

MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencies of 'memory' T cell responses against viruses such as cytomegalovirus (CMV) and Epstein-Barr virus (EBV), and provided information about their phenotypic and functional variation. However, such studies have...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Komatsu, H More by this author
V Cuero, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Journal:
Clinical and experimental immunology
Volume:
134
Issue:
1
Pages:
9-12
Publication date:
2003-10-05
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:176bf23e-9d71-4de2-8ca9-79eba1733e8c
Source identifiers:
13691
Local pid:
pubs:13691

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP