MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencies of 'memory' T cell responses against viruses such as cytomegalovirus (CMV) and Epstein-Barr virus (EBV), and provided information about their phenotypic and functional variation. However, such studies have...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.
If you are the owner of this record, you can report an update to it here: Report update to this record