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NucleoFinder: a statistical approach for the detection of nucleosome positions.

Abstract:

MOTIVATION: The identification of nucleosomes along the chromatin is key to understanding their role in the regulation of gene expression and other DNA-related processes. However, current experimental methods (MNase-ChIP, MNase-Seq) sample nucleosome positions from a cell population and contain biases, making thus the precise identification of individual nucleosomes not straightforward. Recent works have only focused on the first point, where noise reduction approaches have been developed to...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Hancock, JM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics, Clinical Medicine
Journal:
Bioinformatics (Oxford, England)
Volume:
29
Issue:
6
Pages:
711-716
Publication date:
2013-03-05
DOI:
EISSN:
1367-4811
ISSN:
1367-4803
URN:
uuid:174f41f6-dd10-4ce9-aa43-fc2ddaf063d8
Source identifiers:
374245
Local pid:
pubs:374245

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