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Automated assessment of bone changes in cross-sectional micro-CT studies of murine experimental osteoarthritis

Abstract:

OBJECTIVE: The degradation of articular cartilage, which characterises osteoarthritis (OA), is usually paired with excessive bone remodelling, including subchondral bone sclerosis, cysts, and osteophyte formation. Experimental models of OA are widely used to investigate pathogenesis, yet few validated metho...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0174294

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Department:
Oxford, MSD, NDORMS, KIR
More by this author
Department:
Oxford, MSD, NDORMS, KIR
Marenzana, M More by this author

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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
12
Issue:
3
Pages:
e0174294
Publication date:
2017-03-23
Acceptance date:
2017-03-07
DOI:
ISSN:
1932-6203
Pubs id:
pubs:687030
URN:
uri:173db6f0-a44e-4329-93c1-d721db933f03
UUID:
uuid:173db6f0-a44e-4329-93c1-d721db933f03
Local pid:
pubs:687030
Language:
English
Keywords:

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