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Journal article

Genetic causes of hypomagnesemia, a clinical overview.

Abstract:

Magnesium is essential to the proper functioning of numerous cellular processes. Magnesium ion (Mg2+) deficits, as reflected in hypomagnesemia, can cause neuromuscular irritability, seizures and cardiac arrhythmias. With normal Mg2+ intake, homeostasis is maintained primarily through the regulated reabsorption of Mg2+ by the thick ascending limb of Henle’s loop and distal convoluted tubule of the kidney. Inadequate reabsorption results in renal Mg 2+ wasting, as evidenced by an inappropriatel...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s00467-016-3416-3

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Publisher:
Springer Publisher's website
Journal:
Pediatric Nephrology Journal website
Publication date:
2016-05-05
DOI:
EISSN:
1432-198X
ISSN:
0931-041X
URN:
uuid:171a2359-e036-47e7-8f79-a0dac29a28fb
Source identifiers:
633121
Local pid:
pubs:633121

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