Journal article

New MAPS for misfolded proteins

Abstract:: Clearing misfolded proteins from the cytoplasm is essential to maintain cellular homeostasis. Now a parallel clearance system is described that uses the deubiquitinase USP19 to enable secretion of misfolded cytoplasmic proteins when conventional proteasomal degradation is compromised. Misfolding-Associated Protein Secretion (MAPS) has important implications for protein quality control and prion-like transmission.

Publication status:: Published

Peer review status:: Peer reviewed

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Christianson, J., Volkmar, N., & Fenech, E. (2016). New MAPS for misfolded proteins. Nature Cell Biology, 18, 724–726.

MLA Style

Christianson, J, et al. “New MAPS for Misfolded Proteins.” Nature Cell Biology, vol. 18, 2016, pp. 724–26.

Chicago Style

Christianson, J, N Volkmar, and E Fenech. 2016. “New MAPS for Misfolded Proteins.” Nature Cell Biology 18: 724–26.
Print

Access Document

Files:: NCB 2016 News and Views_clean.pdf

(Preview, Accepted manuscript, pdf, 53.1KB, Terms of use)

Publisher copy:: 10.1038/ncb3381

Authors

+ Christianson, J More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

+ Volkmar, N More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

+ Fenech, E More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

Publisher:: Nature Publishing Group
Journal:: Nature Cell Biology More from this journal
Volume:: 18
Pages:: 724–726
Publication date:: 2016-01-01
Acceptance date:: 2016-05-28
DOI:: 10.1038/ncb3381
EISSN:: 1476-4679
ISSN:: 1465-7392

Pubs id:: pubs:625191
UUID:: uuid:17127318-1480-4c68-8305-1e7d1e4cb275
Local pid:: pubs:625191
Source identifiers:: 625191
Deposit date:: 2016-06-03
ARK identifier:: ark:/29072/ora_1712731814804c6883051e7d1e4cb275

Terms of use

Copyright holder:: Macmillan Publishers
Copyright date:: 2016
Notes:: © 2016 Macmillan Publishers Limited. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Nature at: [10.1038/ncb3381]

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP