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Association analysis of the vitamin D receptor gene, the type I collagen gene COL1A1, and the estrogen receptor gene in idiopathic osteoarthritis.

Abstract:

OBJECTIVE: Evidence has accumulated supporting a role for genes in the etiology of osteoarthritis (OA). Several candidates have been targeted as potential susceptibility loci including genes that are involved in the regulation of bone density. Genetic association analysis has suggested a role for the vitamin D receptor gene (VDR) and the estrogen receptor gene (ER) in susceptibility. Such findings must be tested in additional independent cohorts. We tested for association of these 2 genes, pl...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Journal of rheumatology
Volume:
27
Issue:
3
Pages:
779-784
Publication date:
2000-03-01
ISSN:
0315-162X
Source identifiers:
103818
Language:
English
Keywords:
Pubs id:
pubs:103818
UUID:
uuid:17033ff3-ea75-4e92-a330-c77ceff0eb7f
Local pid:
pubs:103818
Deposit date:
2012-12-19

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