Journal article
Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.
- Abstract:
-
Induction of immunity to a viral protein that had been transfected into a tumor cell line was studied. The nucleoprotein (NP) of vesicular stomatitis virus (VSV) was used as a model tumor-associated Ag after transfection into EL-4, and H-2b thymoma originating from C57BL/6 mice. The NP-transfected cell line (EL-4NP) was lysed by NP-specific CTL and was found to restimulate NP-specific CTL in vitro as efficiently as did VSV-infected macrophages. Despite both of these in vitro characteristics, ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 150
- Issue:
- 10
- Pages:
- 4450-4456
- Publication date:
- 1993-05-01
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
469199
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:469199
- UUID:
-
uuid:16f612f1-7753-470d-8739-1b12c090cacb
- Local pid:
- pubs:469199
- Deposit date:
- 2014-06-17
Terms of use
- Copyright date:
- 1993
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