Journal article
Highly diastereoselective ketone aldol reactions of butane-2,3-diacetal desymmetrised glycolic acid
- Abstract:
- Butane-2,3-diacetal (BDA) desymmetrised glycolic acid building block 1 undergoes highly diastereoselective lithium enolate ketone aldol reactions with a range of methyl and mono-substituted methyl ketones to yield, after acid-catalysed deprotection, enantiopure α,β-dihydroxy acid derivatives bearing a quaternary carbon atom at the β-hydroxy centre.
- Publication status:
- Published
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- Publisher copy:
- 10.1055/s-2002-34377
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Bibliographic Details
- Journal:
- SYNTHESIS-STUTTGART
- Volume:
- 2002
- Issue:
- 14
- Pages:
- 1973-1978
- Publication date:
- 2002-01-01
- DOI:
- EISSN:
-
1437-210X
- ISSN:
-
0039-7881
- Source identifiers:
-
52083
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:52083
- UUID:
-
uuid:16ec88a5-d892-43cf-a10c-a2edcdf5ce8f
- Local pid:
- pubs:52083
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2002
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