Journal article

α7-Acetylcholine receptor antibodies in two patients with Rasmussen encephalitis

Abstract:: Rasmussen encephalitis (RE) sera were screened for antibodies to human α7 nicotinic acetylcholine receptors (nAChRs) using electrophysiology, calcium imaging, and ligand binding assays. Sera from two of nine patients with RE blocked ACh-induced currents through α7 nAChRs and the ACh-induced rise in intracellular free calcium ([Ca2+]i) and inhibited 125I-α-bungarotoxin binding in cells expressing α7 nAChRs. Thus, the α7 nAChR is a potential target for pathogenic antibodies in patients with RE. Copyright © 2005 by AAN Enterprises, Inc.

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APA Style

Watson, R., Jepson, J., Bermudez, I., Alexander, S., Hart, Y., McKnight, K., Roubertie, A., Fecto, F., Valmier, J., Sattelle, D., Beeson, D., Vincent, A., & Lang, B. (2005). α7-Acetylcholine receptor antibodies in two patients with Rasmussen encephalitis. Neurology, 65(11), 1802–1804.

MLA Style

Watson, R, et al. “α7-Acetylcholine Receptor Antibodies in Two Patients with Rasmussen Encephalitis.” Neurology, vol. 65, no. 11, 2005, pp. 1802–04.

Chicago Style

Watson, R, J Jepson, I Bermudez, et al. 2005. “α7-Acetylcholine Receptor Antibodies in Two Patients with Rasmussen Encephalitis.” Neurology 65 (11): 1802–4.
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Publisher copy:: 10.1212/01.wnl.0000191566.86977.04

Authors

+ Watson, R More by this author

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+ Jepson, J More by this author

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+ Bermudez, I More by this author

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+ Alexander, S More by this author

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+ Hart, Y More by this author

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Journal:: Neurology More from this journal
Volume:: 65
Issue:: 11
Pages:: 1802-1804
Publication date:: 2005-12-01
DOI:: 10.1212/01.wnl.0000191566.86977.04
ISSN:: 0028-3878

Language:: English
Pubs id:: pubs:242934
UUID:: uuid:16eb8820-4d70-427b-aea6-802ee52a7422
Local pid:: pubs:242934
Source identifiers:: 242934
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_16eb88204d70427baea6802ee52a7422

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Copyright date:: 2005

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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