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Journal article

Separate value comparison and learning mechanisms in macaque medial and lateral orbitofrontal cortex.

Abstract:

Uncertainty about the function of orbitofrontal cortex (OFC) in guiding decision-making may be a result of its medial (mOFC) and lateral (lOFC) divisions having distinct functions. Here we test the hypothesis that the mOFC is more concerned with reward-guided decision making, in contrast with the lOFC's role in reward-guided learning. Macaques performed three-armed bandit tasks and the effects of selective mOFC lesions were contrasted against lOFC lesions. First, we present analyses that make...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.1012246107

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
107
Issue:
47
Pages:
20547-20552
Publication date:
2010-11-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:16d8697c-13c9-42bc-a7a8-0b5bcd8b6e69
Source identifiers:
93205
Local pid:
pubs:93205

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