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Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore.

Abstract:
The four DNA bases are recognized in immobilized DNA strands at high alkaline pH by nanopore current recordings. Ionic currents through the biological nanopores are also employed to measure the apparent pK(a) values of single nucleobases within the immobilised DNA strands.
Publication status:
Published

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Publisher copy:
10.1039/c1cc16124e

Authors


Franceschini, L More by this author
Mikhailova, E More by this author
Journal:
Chemical communications (Cambridge, England)
Volume:
48
Issue:
10
Pages:
1520-1522
Publication date:
2012-02-05
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
URN:
uuid:16c0ec93-2084-47f0-8f8e-78bd2060d631
Source identifiers:
246104
Local pid:
pubs:246104
Language:
English
Keywords:

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