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Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network.

Abstract:

The neural crest is an embryonic stem cell population that gives rise to a multitude of derivatives. In particular, the cranial neural crest (CNC) is unique in its ability to contribute to both facial skeleton and peripheral ganglia. To gain further insight into the molecular underpinnings that distinguish the CNC from other embryonic tissues, we have utilized a CNC-specific enhancer as a tool to isolate a pure, region-specific NC subpopulation for transcriptional profiling. The resulting dat...

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Publication status:
Published

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Publisher copy:
10.1101/gr.161182.113

Authors


Simões-Costa, M More by this author
Tan-Cabugao, J More by this author
Antoshechkin, I More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Bronner, ME More by this author
Journal:
Genome research
Volume:
24
Issue:
2
Pages:
281-290
Publication date:
2014-02-05
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:16bdca66-ca38-410e-9b7f-13630310f66d
Source identifiers:
445785
Local pid:
pubs:445785

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