Journal article

The role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravis.

Abstract:: MuSK myasthenia gravis is a rare, severe autoimmune disease of the neuromuscular junction, only identified in 2001, with unclear pathogenic mechanisms. In this review we describe the clinical aspects that distinguish MuSK MG from AChR MG, review what is known about the role of MuSK in the development and function of the neuromuscular junction, and discuss the data that address how the antibodies to MuSK lead to neuromuscular transmission failure.

Publication status:: Published

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APA Style

Koneczny, I., Cossins, J., & Vincent, A. (2014). The role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravis. Journal of Anatomy, 224(1), 29–35.

MLA Style

Koneczny, I., et al. “The Role of Muscle-Specific Tyrosine Kinase (MuSK) and Mystery of MuSK Myasthenia Gravis.” Journal of Anatomy, vol. 224, no. 1, 2014, pp. 29–35.

Chicago Style

Koneczny, I, J Cossins, and A Vincent. 2014. “The Role of Muscle-Specific Tyrosine Kinase (MuSK) and Mystery of MuSK Myasthenia Gravis.” Journal of Anatomy 224 (1): 29–35.
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Publisher copy:: 10.1111/joa.12034

Authors

+ Koneczny, I More by this author

Role:

Author

+ Cossins, J More by this author

Role:

Author

+ Vincent, A More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Clinical Neurosciences

Role:

Author

Bibliographic Details

Journal:: Journal of anatomy More from this journal
Volume:: 224
Issue:: 1
Pages:: 29-35
Publication date:: 2014-01-01
DOI:: 10.1111/joa.12034
EISSN:: 1469-7580
ISSN:: 0021-8782

Item Description

Language:: English
Keywords:: Autoantibodies

Myasthenia Gravis

Receptors, Cholinergic

Humans

Receptor Protein-Tyrosine Kinases

Neuromuscular Junction
Pubs id:: pubs:387869
UUID:: uuid:16a6e04a-8dd3-42a8-a71a-507a98452c57
Local pid:: pubs:387869
Source identifiers:: 387869
Deposit date:: 2013-11-16

Terms of use

Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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