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Journal article

Fluorescence in situ hybridization analysis of circulating tumor cells in metastatic prostate cancer.

Abstract:

PURPOSE: To assess the feasibility of characterizing gene copy number alteration by fluorescence in situ hybridization (FISH) of circulating tumor cells (CTC) isolated using the CellSearch system in patients with progressive castration-resistant metastatic prostate cancer. EXPERIMENTAL DESIGN: We used probe combinations that included the androgen receptor (AR) and MYC genes for FISH analysis of CTC samples collected from 77 men with castration-resistant metastatic prostate cancer. RESULTS: Hi...

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Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
15
Issue:
6
Pages:
2091-2097
Publication date:
2009-03-05
DOI:
EISSN:
1557-3265
ISSN:
1078-0432
URN:
uuid:16506230-e70f-4d33-9e9e-228ebded045c
Source identifiers:
365918
Local pid:
pubs:365918

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