- Abstract:
-
PURPOSE: To assess the feasibility of characterizing gene copy number alteration by fluorescence in situ hybridization (FISH) of circulating tumor cells (CTC) isolated using the CellSearch system in patients with progressive castration-resistant metastatic prostate cancer. EXPERIMENTAL DESIGN: We used probe combinations that included the androgen receptor (AR) and MYC genes for FISH analysis of CTC samples collected from 77 men with castration-resistant metastatic prostate cancer. RESULTS: Hi...
Expand abstract - Publisher copy:
- 10.1158/1078-0432.ccr-08-2036
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- Journal:
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Volume:
- 15
- Issue:
- 6
- Pages:
- 2091-2097
- Publication date:
- 2009-03-05
- DOI:
- EISSN:
-
1557-3265
- ISSN:
-
1078-0432
- URN:
-
uuid:16506230-e70f-4d33-9e9e-228ebded045c
- Source identifiers:
-
365918
- Local pid:
- pubs:365918
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
Fluorescence in situ hybridization analysis of circulating tumor cells in metastatic prostate cancer.
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