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Journal article

Neglect of Plasmodium vivax malaria.

Abstract:
Plasmodium vivax infects 130-435 million of the 2.6 billion people living at risk of infection. Recent studies suggest that vivax malaria can become lethal in a similar way to severe falciparum malaria. First-line therapies remain unchanged after 50 years. Despite evidence of failing chloroquine efficacy, little work has assessed the problem or explored alternative therapies. Primaquine treatment, the only therapeutic option against relapse, might also be failing. No licensed primary chemoprophylactic agent protects travelers from relapse. Misdiagnosis of species now affects clinical decisions resulting in inadequate therapy for P. falciparum and P. vivax. All of these factors demonstrate the lack of research on P. vivax.
Publication status:
Published

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Publisher copy:
10.1016/j.pt.2007.08.011

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author


Journal:
Trends in parasitology More from this journal
Volume:
23
Issue:
11
Pages:
533-539
Publication date:
2007-11-01
DOI:
EISSN:
1471-5007
ISSN:
1471-4922


Language:
English
Keywords:
Pubs id:
pubs:81642
UUID:
uuid:1618952f-bb52-4e78-acd2-373c5ac392a9
Local pid:
pubs:81642
Source identifiers:
81642
Deposit date:
2012-12-19
ARK identifier:

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