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Structure and expression of an Otx5-related gene in the dogfish Scyliorhinus canicula: evidence for a conserved role of Otx5 and Crxgenes in the specification of photoreceptors.

Abstract:

We report the full-length coding sequence and the expression pattern during neurulation and early organogenesis of ScOtx5, a novel member of the Otx gene family in the dogfish Scyliorhinus canicula. Phylogenetic analyses confirm that ScOtx5 is closely related to the Xenopus XlOtx5/ 5bgenes, and also to the Crx genes characterized in mammals and zebrafish. This supports the hypothesis that these genes define a third gnathostome Otx orthology class. During neurulation, ScOtx5 transcripts are de...

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Publisher copy:
10.1007/s00427-001-0191-2

Authors


Journal:
Development genes and evolution
Volume:
211
Issue:
11
Pages:
533-544
Publication date:
2001-12-05
DOI:
EISSN:
1432-041X
ISSN:
0949-944X
URN:
uuid:16130651-fb28-497b-a2c7-0df924189582
Source identifiers:
265680
Local pid:
pubs:265680

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