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Journal article

The pathophysiology of the intervertebral disc.

Abstract:
After a review of disk structure, the pivotal role of disk cells in producing and renewing the extracellular disk matrix is emphasized. Disk cells rely on nutrients that diffuse through the vertebral endplates. Microelectrode methods have been developed to study nutrient diffusion and endplate permeability. Mechanical stimuli modify disk cell activity. Scoliosis is associated with decreased endplate permeability, a factor that may play a role in disk degeneration and scoliosis progression.
Publication status:
Published

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Publisher copy:
10.1016/s1297-319x(01)00332-3

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Journal:
Joint, bone, spine : revue du rhumatisme More from this journal
Volume:
68
Issue:
6
Pages:
537-542
Publication date:
2001-12-01
DOI:
EISSN:
1778-7254
ISSN:
1297-319X


Language:
English
Keywords:
Pubs id:
pubs:238016
UUID:
uuid:16040fdc-0761-4a85-b6fc-5082dc35ce5e
Local pid:
pubs:238016
Source identifiers:
238016
Deposit date:
2013-11-16
ARK identifier:

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