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Journal article

MRI brain T1 relaxation time changes in MS patients increase over time in both the white matter and the cortex.

Abstract:

OBJECTIVE: To test the sensitivity of whole-brain T1 relaxometry to the evolution of pathological changes in multiple sclerosis (MS). BACKGROUND: T1-weighted hypointense lesion load in the brains of patients with MS is associated with axonal loss. Other work has shown that T1 measurements may provide information complementary to existing imaging techniques, such as magnetization transfer imaging. METHODS: The authors studied 14 MS patients twice over a median time interval of 19.5 months (ra...

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Publication status:
Published

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Publisher copy:
10.1177/1051228403013003006

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Journal:
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Volume:
13
Issue:
3
Pages:
234-239
Publication date:
2003-07-05
DOI:
EISSN:
1552-6569
ISSN:
1051-2284
URN:
uuid:15e0388b-62f6-4303-9e20-d135c20bc740
Source identifiers:
116314
Local pid:
pubs:116314

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