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Effects of S-adenosylmethionine decarboxylase, polyamines, amino acids, and weak bases (amines and ammonia) on development and ribosomal RNA synthesis in Xenopus embryos.

Abstract:

We have been studying control mechanisms of gene expression in early embryogenesis in a South African clawed toad Xenopus laevis, especially during the period of midblastula transition (MBT), or the transition from the phase of active cell division (cleavage stage) to the phase of extensive morphogenesis (post-blastular stages). We first found that ribosomal RNA synthesis is initiated shortly after MBT in Xenopus embryos and those weak bases, such as amines and ammonium ion, selectively inhib...

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Publisher copy:
10.1007/s00726-009-0403-z

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Journal:
Amino acids
Volume:
38
Issue:
2
Pages:
439-449
Publication date:
2010-02-05
DOI:
EISSN:
1438-2199
ISSN:
0939-4451
URN:
uuid:15ccf1f6-2323-4424-81e0-73cb63940167
Source identifiers:
259418
Local pid:
pubs:259418

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