Conservation, error and dynamics in protein interaction networks.
The availability of large scale protein interaction networks for several species has motivated many comparative studies in recent years. These studies typically employ network alignment algorithms for the task and use the sequence similarity of proteins to aid the alignment process. In this thesis I use a quantitative measure of protein functional similarity and show that the results are superior to sequence based network alignment. I present a method for module detection that combines result...Expand abstract
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- Oxford University, UK
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- Ali, W
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- For copyright reasons some figures have been removed from this digital version of the thesis.
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