Dimensional, geometrical, and physical constraints in skull growth

Journal article

After birth, the skull grows and remodels in close synchrony with the brain to allow for an increase in intracranial volume. Increase in skull area is provided primarily by bone accretion at the sutures. Additional remodeling, to allow for a change in curvatures, occurs by resorption on the inner surface of the bone plates and accretion on their outer surfaces. When a suture fuses too early, normal skull growth is disrupted, leading to deformed final skull shape. The leading theory assumes that the main stimulus for skull growth is provided by mechanical stresses. Based on these ideas, we first discuss the dimensional, geometrical, and kinematics synchrony between brain, skull and suture growth. Second, we present two mechanical models for skull growth that account for growth at the sutures and explain the various observed dysmorphologies. These models demonstrate the particular role of physical and geometrical constraints taking place in skull growth.

Authors: Weickenmeier, J; Fischer, C; Carter, D; Kuhl, E; Goriely, A

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: American Physical Society
• Journal: Physical Review Letters
• Volume: 118
• Pages: 248101
• Publication date: 2017-06-01
• Acceptance date: 2017-05-19
• DOI: 10.1103/PhysRevLett.118.248101
• ISSN: 0031-9007 and 1079-7114