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A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite.

Abstract:

As a consequence of gene cloning and DNA sequencing several gene families are emerging in the field of cell-cell recognition. These include immunoglobulins, integrins, certain extracellular glycoproteins and a family of functionally unrelated proteins which include factor B. We report here the cloning and sequencing of a gene from Plasmodium falciparum, coding for a protein we call thrombospondin related anonymous protein (TRAP), which shares certain sequence motifs common to other well-chara...

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Publication status:
Published

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Publisher copy:
10.1038/335079a0

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Journal:
Nature
Volume:
335
Issue:
6185
Pages:
79-82
Publication date:
1988-09-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:15bb2b0c-2972-44ba-89c2-f013ea6e4391
Source identifiers:
20977
Local pid:
pubs:20977

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