Journal article
Disentangling the relationship between Lewy bodies and nigral neuronal loss in Parkinson's disease
- Abstract:
-
Progressive rostral spread of Lewy body (LB) pathology is thought to reflect the clinical course of Parkinson's disease (PD) although several studies have suggested that LBs are not the toxic species responsible for cell death. We investigated the relationship between nigral dopaminergic cell loss, distribution and density of α-synuclein-immunoreactive LBs and duration of motor symptoms in 97 patients with PD. Density of pigmented neurons was measured in a single section of one half of the su...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- IOS Press
- Journal:
- Journal of Parkinson's Disease More from this journal
- Volume:
- 1
- Issue:
- 3
- Pages:
- 277-286
- Publication date:
- 2011-03-01
- Acceptance date:
- 2010-01-01
- DOI:
- ISSN:
-
1877-718X
Item Description
- Keywords:
- Pubs id:
-
pubs:579202
- UUID:
-
uuid:15b57520-416e-4f66-9370-c4384c42896b
- Local pid:
-
pubs:579202
- Source identifiers:
-
579202
- Deposit date:
-
2015-12-09
Terms of use
- Copyright holder:
- Parkkinen et al
- Copyright date:
- 2011
- Notes:
- © 2011 – IOS Press and the authors. All rights reserved
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