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Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator.

Abstract:

BACKGROUND: A significant reduction in parasite clearance rates following artesunate treatment of falciparum malaria, and increased failure rates following artemisinin combination treatments (ACT), signaled emergent artemisinin resistance in Western Cambodia. Accurate measurement of parasite clearance is therefore essential to assess the spread of artemisinin resistance in Plasmodium falciparum. The slope of the log-parasitaemia versus time relationship is considered to be the most robust mea...

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Publication status:
Published

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Publisher copy:
10.1186/1475-2875-10-339

Authors


Guerin, PJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Stepniewska, K More by this author
Journal:
Malaria journal
Volume:
10
Issue:
1
Pages:
339
Publication date:
2011
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:15abb5b4-afa3-4748-b3db-eb157da68cbd
Source identifiers:
206037
Local pid:
pubs:206037

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