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Analysis of allele-specific gene expression.

Abstract:

The analysis of allele-specific gene expression has been of long-standing interest in the study of genomic imprinting, but there is growing awareness that differences in allelic expression are widespread among autosomal nonimprinted genes. Recent research into cis-acting regulatory polymorphisms has utilized the analysis of allele-specific gene expression to identify functionally important regulatory haplotypes and specific genetic polymorphisms. Allele-specific effects are typically of modes...

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Publisher copy:
10.1385/1-59745-097-9:153

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
338
Pages:
153-165
Publication date:
2006
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
URN:
uuid:158acece-46a3-4698-9132-72af56f8db4b
Source identifiers:
29932
Local pid:
pubs:29932

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