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Journal article

Association of the APOE epsilon4 allele with disease activity in multiple sclerosis.

Abstract:

OBJECTIVES: Allelic variants of the APOE gene are known to influence the course of many neurological diseases and there is increasing evidence that apolipoprotein E (APOE) is a pivotal component in reinnervation and dendritic remodelling after neuronal injury. Previous studies did not show significant differences in the APOE allele frequencies in multiple sclerosis compared with controls but did not examine for correlation with disease severity. This study explores the relation of APOE genoty...

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Publication status:
Published

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Publisher copy:
10.1136/jnnp.67.2.203

Authors


Evangelou, N More by this author
Jackson, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Journal:
Journal of neurology, neurosurgery, and psychiatry
Volume:
67
Issue:
2
Pages:
203-205
Publication date:
1999-08-05
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
URN:
uuid:1570d324-c7f1-4bdc-9200-1174f6d4cd16
Source identifiers:
387046
Local pid:
pubs:387046

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