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Detection of vaccine-induced antibodies to Ebola virus in oral fluid

Abstract:
Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ofid/ofw031

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author


Publisher:
Oxford University Press
Journal:
Open forum infectious diseases More from this journal
Volume:
3
Issue:
1
Pages:
ofw031
Publication date:
2016-02-22
Acceptance date:
2016-02-05
DOI:
EISSN:
2328-8957


Language:
English
Keywords:
Pubs id:
pubs:611791
UUID:
uuid:15673dd1-fc52-48c5-a5ca-8054da26b3f9
Local pid:
pubs:611791
Source identifiers:
611791
Deposit date:
2016-06-23
ARK identifier:

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