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Detection of vaccine-induced antibodies to Ebola virus in oral fluid

Abstract:
Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/ofid/ofw031

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
Rampling, T More by this author
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Publisher:
Oxford University Press Publisher's website
Journal:
Open forum infectious diseases Journal website
Volume:
3
Issue:
1
Pages:
ofw031
Publication date:
2016-02-22
Acceptance date:
2016-02-05
DOI:
EISSN:
2328-8957
URN:
uuid:15673dd1-fc52-48c5-a5ca-8054da26b3f9
Source identifiers:
611791
Local pid:
pubs:611791
Language:
English
Keywords:

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