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Potassium channels: structures, models, simulations.

Abstract:

Potassium channels have been studied intensively in terms of the relationship between molecular structure and physiological function. They provide an opportunity to integrate structural and computational studies in order to arrive at an atomic resolution description of mechanism. We review recent progress in K channel structural studies, focussing on the bacterial channel KcsA. Structural studies can be extended via use of computational (i.e. molecular simulation) approaches in order to provi...

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Publication status:
Published

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Authors


Sansom, MS More by this author
Shrivastava, IH More by this author
Bright, JN More by this author
Capener, CE More by this author
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Journal:
Biochimica et biophysica acta
Volume:
1565
Issue:
2
Pages:
294-307
Publication date:
2002-10-05
DOI:
ISSN:
0006-3002
URN:
uuid:155b66ed-3abf-4c9c-8ac9-a879abc5dd91
Source identifiers:
100188
Local pid:
pubs:100188

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