Journal article icon

Journal article

Calcium, diet and fracture risk: a prospective study of 1898 incident fractures among 34696 British women and men

Abstract:
Objective: The risk factors for fractures are incompletely understood. An outstanding question concerns the optimal amount of dietary calcium needed to minimise the risk of fracture. Design: We examined the associations of dietary calcium and other nutrients with self-reported fracture risk in a prospective cohort study. Nutrient intakes were estimated using a semi-quantitative food-frequency questionnaire administered at recuitment. Setting: The UK. Participants: A total of 26749 women and 7947 men aged 20-89 years. Results: Over an average of 5.2 years of follow-up, 1555 women and 343 men reported one or more fractures, 72% of these resulting from a fall. Among women, fracture risk was higher at lower calcium intakes, with a relative risk of 1.75 (95% confidence interval (CI) 1.33-2.29) among woment with a calcium intake of < 525 mg day -1 compared with women with a calcium intake of at least 1200 mg day -1 (test for linear trend, P < 0.001). The association of dietary calcium with fracture risk was stronger among women aged under 50 at recruitment than among women aged 50 and above. Dietary calcium intake was not associated with fracture risk in men. Fracture risk was not relate to the dietary intake of any other nutrient examined. Conclusion: In this population, women with a low dietary calcium intake had an increased risk of bone fracture, and this association was more marked among younger women than among older women.
Publication status:
Published
Peer review status:
Peer reviewed

Actions

Access Document

Publisher copy:
10.1017/S1368980007696402

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
Viertel Centre for Research in Cancer Control, Queensland Cancer Fund, Queensland, Australia
Role:
Author

Contributors


Publisher:
Cambridge University Press
Journal:
Public Health Nutrition More from this journal
Volume:
10
Issue:
11
Pages:
1314-1320
Publication date:
2007-01-01
DOI:
EISSN:
1475-2727
ISSN:
1368-9800


Language:
English
Keywords:
Subjects:
UUID:
uuid:15487dd6-de71-46aa-8c1a-5829e0d3da74
Local pid:
ora:4461
Deposit date:
2010-11-17
ARK identifier:

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP