Journal article
T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation.
- Abstract:
-
Recognition of peptide antigen by T cells involves coordinated movement of T cell receptors (TCRs) along with other costimulatory and signaling molecules. The spatially organized configurations that result are collectively referred to as the immunological synapse. Experimental investigation of the role of spatial organization in TCR signaling has been facilitated by the use of nanopatterned-supported membranes to direct TCR into alternative patterns. Here we study the mechanism by which subst...
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- Publisher copy:
- 10.1529/biophysj.107.119099
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Authors
Bibliographic Details
- Journal:
- Biophysical journal
- Volume:
- 94
- Issue:
- 8
- Pages:
- 3286-3292
- Publication date:
- 2008-04-01
- DOI:
- EISSN:
-
1542-0086
- ISSN:
-
0006-3495
- Source identifiers:
-
426322
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:426322
- UUID:
-
uuid:15344b9c-8fce-4ba3-b551-9d8ac6cb4bec
- Local pid:
- pubs:426322
- Deposit date:
- 2014-07-10
Terms of use
- Copyright date:
- 2008
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