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Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma.

Abstract:

BACKGROUND: Noneosinophilic asthma is common across asthma severities. However, in patients with moderate-to-severe disease, the absence of sputum eosinophilia cannot distinguish between asthmatic subjects with eosinophilic inflammation controlled by corticosteroids versus those in whom eosinophilic inflammation is not a component of the disease. OBJECTIVES: We sought to develop a method to quantify eosinophil proteins in airway macrophages as a novel biomarker of eosinophilic airway inflamma...

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Publisher copy:
10.1016/j.jaci.2010.03.026

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Journal:
The Journal of allergy and clinical immunology
Volume:
126
Issue:
1
Pages:
61-9.e3
Publication date:
2010-07-05
DOI:
EISSN:
1097-6825
ISSN:
0091-6749
URN:
uuid:1506131e-65b9-41ca-95ef-d71b357088ef
Source identifiers:
423815
Local pid:
pubs:423815

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