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Specific human cytotoxic T cells recognize B-cell lines persistently infected with respiratory syncytial virus.

Abstract:

The T-lymphocyte response to respiratory syncytial (RS) virus has been invoked to explain the bronchiolitis and pneumonia caused by RS virus in human infants. However, T cells also appear to play a role in protection against RS virus infection. Although RS virus-specific human lymphocytes have been demonstrated, neither the phenotype nor the function of the lymphocytes was characterized. We describe here the induction of anti-RS virus cytotoxic T lymphocytes, in both bulk culture and restimul...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.83.23.9183

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
83
Issue:
23
Pages:
9183-9187
Publication date:
1986-12-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
42651

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