- Abstract:
-
In a study of mainly paucibacillary leprosy-affected sib-pair families from South India, in addition to the expected associations with the HLA-DRB1 locus, we have identified significant association with a functional variant of the MICA gene as well as a microsatellite in the flanking region of the MICB gene. The associations with MICA and MICB cannot be accounted for by linkage disequilibrium with the HLA class II locus indicating a role in genetic susceptibility to leprosy that is independen...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/hmg/ddl229
-
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- Journal:
- Human molecular genetics
- Volume:
- 15
- Issue:
- 19
- Pages:
- 2880-2887
- Publication date:
- 2006-10-05
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- URN:
-
uuid:14d79485-95f6-40e8-86a7-3416e41288e1
- Source identifiers:
-
33583
- Local pid:
- pubs:33583
- Copyright date:
- 2006
Journal article
Variation in MICA and MICB genes and enhanced susceptibility to paucibacillary leprosy in South India.
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