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Improved spectral resolution and high reliability of in vivo $^1$H MRS at 7 T allow the characterization of the effect of acute exercise on carnosine in skeletal muscle

Abstract:

The aims of this study were to observe the behavior of carnosine peaks in human soleus (SOL) and gastrocnemius (GM) muscles following acute exercise, to determine the relaxation times and to assess the repeatability of carnosine quantification by 1H MRS at 7 T. Relaxation constants in GM and SOL were measured by a stimulated echo acquisition mode (STEAM) localization sequence. For T1 measurement, an inversion recovery sequence was used. The repeatability of the measurement and the absolute qu...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/nbm.3447

Authors


Just Kukurová, I More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
Ukropec, J More by this author
de Courten, B More by this author
Chmelík, M More by this author
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Grant:
#14587, #15455, #15363
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Grant:
Sir Henry Dale Fellowship
Publisher:
John Wiley and Sons Ltd. Publisher's website
Journal:
NMR in Biomedicine Journal website
Volume:
29
Issue:
1
Pages:
24-32
Publication date:
2016-01-05
DOI:
ISSN:
0952-3480
URN:
uuid:14c6b490-4a1f-4857-850a-098f47035944
Source identifiers:
581528
Local pid:
pubs:581528

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