Proceedings of research in clinical practice 2011.
The skeletal muscle proteins, dysferlin (DYSF) and myoferlin (MYOF) have been demonstrated by mass spectrometry to be present in the apical syncytiotrophoblast of the human placenta, where they may play a role in membrane repair. Immunohistochemistry and immunoblotting were performed on placental samples to localize and quantify DYSF and MYOF in first trimester, term and pathological pregnancies. Here, we show that placental DYSF and MYOF are reduced in labour but only MYOF is elevated in cas...Expand abstract
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