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Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants.

Abstract:

OBJECTIVES: Infants infected with HIV-1 perinatally despite single-dose nevirapine progress rapidly. Data on treatment outcome in sub-Saharan African infants exposed to single-dose nevirapine are urgently required. This feasibility study addresses efficacy of infant antiretroviral therapy in this setting. METHODS: HIV-infected infants in Durban, South Africa, received randomized immediate or deferred (when CD4 cell count reached <20%) four-drug antiretroviral therapy (zidovudine/lamivudine...

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Publication status:
Published

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Authors


Prendergast, A More by this author
Mphatswe, W More by this author
Tudor-Williams, G More by this author
Rakgotho, M More by this author
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Journal:
AIDS (London, England)
Volume:
22
Issue:
11
Pages:
1333-1343
Publication date:
2008-07-05
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
URN:
uuid:14b90fcd-2a68-4dbc-93fe-28b8ac4b6a4a
Source identifiers:
190952
Local pid:
pubs:190952

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