- Abstract:
-
BACKGROUND: Pig islets are characterized by significant fragility, preventing successful islet culture prior to xenotransplantation. To improve outcome after culture, we compared the effects of glutamine supplementation on survival and viability of isolated pig islets during culture. METHODS: Pig islets were suspended in CMRL 1066 supplemented either with 2.5 mmol/L N-acetyl-L-alanyl-L-glutamine (NALG), a stable compound of L-glutamine, or with 2.5 or 5.0 mmol/L of free L-glutamine (L-Glu). A...
Expand abstract - Publisher copy:
- 10.1016/j.transproceed.2005.09.043
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- Journal:
- Transplantation proceedings
- Volume:
- 37
- Issue:
- 8
- Pages:
- 3519-3520
- Publication date:
- 2005-10-05
- DOI:
- EISSN:
-
1873-2623
- ISSN:
-
0041-1345
- URN:
-
uuid:14acc61c-9402-4045-824e-4ff5bd7a6570
- Source identifiers:
-
273307
- Local pid:
- pubs:273307
- Language:
- English
- Keywords:
- Copyright date:
- 2005
Journal article
Effect of stable glutamine compounds on porcine islet culture.
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