Journal article
Bacteriophage biopanning in human tumour biopsies to identify cancer-specific targeting ligands.
- Abstract:
-
Intravenous targeting of anticancer agents should improve both efficacy and therapeutic index. However, rational design of targeting constructs requires detailed definition of receptor targets and must take account of polarised tissue architecture that may restrict access to chosen receptors from the bloodstream. Bacteriophage biopanning provides a solution to this problem, identifying targeting sequences by functional selection rather than design, although reiterative panning in polarized hu...
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- Publisher copy:
- 10.1080/10611860701195510
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Bibliographic Details
- Journal:
- Journal of drug targeting
- Volume:
- 15
- Issue:
- 4
- Pages:
- 311-319
- Publication date:
- 2007-05-01
- DOI:
- EISSN:
-
1029-2330
- ISSN:
-
1061-186X
- Source identifiers:
-
178487
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:178487
- UUID:
-
uuid:14a97e64-1174-44e1-9052-9c1b324ae63a
- Local pid:
- pubs:178487
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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