Journal article icon

Journal article

With phases: how two wrongs can sometimes make a right.

Abstract:

In isolation, both weak isomorphous/anomalous difference signals from heavy-atom derivatization and phases from partial molecular-replacement solutions for a subset of the asymmetric unit often fall short of producing interpretable electron-density maps. Phases generated from very partial molecular-replacement models (if generated carefully) can be used to reliably locate heavy-atom sites, even if the signal is not sufficiently strong to allow robust finding of the sites using Patterson inter...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1107/s0907444909048112

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Acta crystallographica. Section D, Biological crystallography
Volume:
66
Issue:
Pt 4
Pages:
420-425
Publication date:
2010-04-01
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
Source identifiers:
52660
Language:
English
Keywords:
Pubs id:
pubs:52660
UUID:
uuid:1498846c-471e-4989-b0e5-84a7865b7023
Local pid:
pubs:52660
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP