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With phases: how two wrongs can sometimes make a right.

Abstract:

In isolation, both weak isomorphous/anomalous difference signals from heavy-atom derivatization and phases from partial molecular-replacement solutions for a subset of the asymmetric unit often fall short of producing interpretable electron-density maps. Phases generated from very partial molecular-replacement models (if generated carefully) can be used to reliably locate heavy-atom sites, even if the signal is not sufficiently strong to allow robust finding of the sites using Patterson inter...

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Publication status:
Published

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Publisher copy:
10.1107/s0907444909048112

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Johnson, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Acta crystallographica. Section D, Biological crystallography
Volume:
66
Issue:
Pt 4
Pages:
420-425
Publication date:
2010-04-05
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
URN:
uuid:1498846c-471e-4989-b0e5-84a7865b7023
Source identifiers:
52660
Local pid:
pubs:52660

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