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Leukemia inhibitory factor is linked to regulatory transplantation tolerance.

Abstract:

BACKGROUND: The specific regulation of allo-tolerance in vivo occurs within a complex microenvironment and involves co-operation between a small proportion of different cell types within the spleen or draining lymph node. By analyzing unmanipulated whole spleen cell populations we have aimed to mimic this in vivo situation to identify critical signaling molecules in regulatory allo-tolerance. METHODS: We compared the kinetics of cytokine release and induction of signaling proteins in (BALB/c...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Transplantation
Volume:
79
Issue:
6
Pages:
726-730
Publication date:
2005-03-01
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
Source identifiers:
55459
Language:
English
Keywords:
Pubs id:
pubs:55459
UUID:
uuid:147a88c5-4259-44da-aec0-716164fb5df4
Local pid:
pubs:55459
Deposit date:
2012-12-19

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